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	Provedor de dados Genet. Mol. Biol. (1) Autor Cólus,Ilce Mara de Syllos (1) D’Arce,Luciana Paula Grégio (1) Losi-Guembarovski,Roberta (1) Palavra-chave Age (1) Brazilian population (1) Control individuals (1) Glutathione S-transferase Mu (GSTM1) (1) Smoking habit (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2002 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Glutathione S-transferase Mu (GSTM1) null genotype in relation to gender, age and smoking status in a healthy Brazilian population Genet. Mol. Biol. Losi-Guembarovski,Roberta; D’Arce,Luciana Paula Grégio; Cólus,Ilce Mara de Syllos. The glutathione S-transferase mu (GSTM1) gene which acts during phase II of xenobiotic metabolism is polymorphic in the population, being absent in about 30-50% of individuals depending on the ethnic group from which they come. Epidemiological studies suggest that individuals who are homozygous null at the GSTM1 locus may have an increased risk of developing various types of neoplastic disease. We used the polymerase chain reaction (PCR) to estimate the frequency of GSTM1 in 176 healthy individuals from the north of Paraná (Brazilian state), the null genotype being detected in 48.86% of these individuals. The Student’s t-test was used to evaluate the frequency of the glutathione S-transferase null genotype in relation to age, gender and smoking habit and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Glutathione S-transferase Mu (GSTM1); Control individuals; Brazilian population; Age; Smoking habit. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572002000400001 Registros recuperados: 1 Primeira ... 1 ... Última

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